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State filing guide

CLIA waiver application and requirements in North Carolina.

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North Carolina publishes an email route for signed CMS-116 applications.

Sources checked 2026-09-10 · next source check due 2026-10-10

Federal application procedure

These findings describe the linked sources. They do not establish that your facility qualifies for an exemption or that its application is ready. Facility type, ownership, personnel, locations and exact test systems can change the requirements.

What the official sources say

  • DHSR provides CMS-116 application and email submission instructions.
  • Special testing programs must be checked against the actual menu rather than inferred from a generic waived-test label.

Fees and timing

Check the current agency fee notice and fee schedule. Government fees are separate from preparation-service fees. This source summary does not promise a processing or approval date.

Check my test menu

What still needs confirmation for your facility

  1. 1Confirm the exact menu and current receiving address for the initial single-site application.

Frequently asked questions

What filing route does the cited North Carolina guidance describe?

North Carolina publishes an email route for signed CMS-116 applications.

Which requirements are named in the cited North Carolina materials?

DHSR provides CMS-116 application and email submission instructions. Special testing programs must be checked against the actual menu rather than inferred from a generic waived-test label.

What do the sources establish about fees and timing in North Carolina?

Check the current agency fee notice and fee schedule. Government fees are separate from preparation-service fees. This source summary does not promise a processing or approval date.

Does this page confirm CLIA approval or legal compliance in North Carolina?

No. This is an educational prep checklist. It does not confirm approval, legal compliance, or waived status for any specific device. Verify every requirement with CMS, the FDA, and your state agency before testing.

Other jurisdictions

Each jurisdiction publishes its own terminology, forms, channel, signatures, and fees.

All 52jurisdictions →

Official sources behind this guide

Need help with your North Carolina CLIA route?

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From test research to your North Carolina application

An analyte label does not confirm a device. The exact test system and the clinic’s state route need separate review before a filing scope or price can be confirmed.